Thousands of unvaccinated Big Apple city workers are set to lose their jobs Friday, which marks the end of the grace period to get a COVID-19 jab.

Nearly 4,000 of the city’s roughly 400,000 municipal employees are currently at risk of getting axed under the mandate made by the de Blasio administration in October.

Current Mayor Eric Adams confirmed this week that he will go ahead with the terminations despite legal objections and a swell of protests, including a march to City Hall planned for early Friday.

The latest figures show that around 95 percent of the city’s workforce have received at least one dose of the vaccine, up from 84 percent when the mandate was announced by then-Mayor Bill de Blasio.

Of those likely to lose their jobs, Adams has repeatedly stressed that he wants to keep them, singling out police officers, firefighters and teachers.

Thousands of NYC workers to lose jobs Friday as vaccine deadline ends.